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TVAX®’s second candidate (TVI-Kidney-1) is being evaluated for the treatment of kidney cancer and targets stage 4 renal cell carcinoma. 

As with TVI-Brain-1, this drug candidate is supported by positive Phase 2 clinical data, as well as extensive preclinical and Phase 1 safety studies.

Several independent clinical studies have validated the potential of TVI-Kidney-1 in treating patients with stage IV renal cell carcinoma.  Data from an independent Phase 2 trial in 39 newly diagnosed stage IV renal cell carcinoma patients demonstrated a significant number of clinical responses (n=9), each of which was associated with significantly prolonged survival.  Additionally, the overall survival for the 39 enrolled patients was prolonged compared to a historical control group (n=81).